@InProceedings{10.1007/978-3-030-00949-6_28, author="Sun, Xu and Xu, Yanwu and Tan, Mingkui and Fu, Huazhu and Zhao, Wei and You, Tianyuan and Liu, Jiang", editor="Stoyanov, Danail and Taylor, Zeike and Ciompi, Francesco and Xu, Yanwu and Martel, Anne and Maier-Hein, Lena and Rajpoot, Nasir and van der Laak, Jeroen and Veta, Mitko and McKenna, Stephen and Snead, David and Trucco, Emanuele and Garvin, Mona K. and Chen, Xin Jan and Bogunovic, Hrvoje", title="Localizing Optic Disc and Cup for Glaucoma Screening via Deep Object Detection Networks", booktitle="Computational Pathology and Ophthalmic Medical Image Analysis", year="2018", publisher="Springer International Publishing", address="Cham", pages="236--244", abstract="Segmentation of the optic disc (OD) and optic cup (OC) from a retinal fundus image plays an important role for glaucoma screening and diagnosis. However, most existing methods only focus on pixel-level representations, and ignore the high level representations. In this work, we consider the high level concept, i.e., objectness constraint, for fundus structure analysis. Specifically, we introduce a deep object detection network to localize OD and OC simultaneously. The end-to-end architecture guarantees to learn more discriminative representations. Moreover, data from a similar domain can further contributes to our algorithm through transfer learning techniques. Experimental results show that our method achieves state-of-the-art OD and OC segmentation/localization results on ORIGA dataset. Moreover, the proposed method also obtains satisfactory glaucoma screening performance with the calculated vertical cup-to-disc ratio (CDR).", isbn="978-3-030-00949-6" }